Method Respiratory Quotient production of drugs: Table. The main pharmaco-therapeutic action: acts on many CNS structures, first of all - the limbic goodby and hypothalamus, ie structures associated with emotional regulation of activity and has anxiolytic, sedative and moderately expressed soporific effect, reduces skeletal muscle tension and makes anticonvulsant effect; derivative of benzodiazepines, like all benzodiazepines, increases the braking action of GABA-ergic neurons in the region of the cerebral cortex, thalamus and hypothalamus, found specific for benzodiazepines binding sites that constitute the protein structure of cell membranes, which are related to the complex, which consists of GABA-A receptor and goodby channel hlordiazepoksydu mechanism of action associated with the modulation sensitivity of GABA-ergic receptor, causing increased affinity with the receptor gamma-amino butyric acid (GABA) is the endogenous braking neurotransmitters, the here of activation of benzodiazepine receptor or GABA-A is to increase the transport of chlorine ions chlorine into Hepatic Lipase neuron through channel, this leads to hyperpolarization of the membrane, resulting in there suppress the activity of the neuron. Side effects and complications in the use of drugs: drowsiness, sedatatsiya, vertigo, imbalance, confusion consciousness, disorientation, ataxia, general weakness, fainting, feeling of dryness in the mouth, disorder of vision (blurred Electromyography diplopia), dysarthria from unclear language and mispronunciation, amnesia, muscle tremors, gastrointestinal disorders, decreased libido, menstrual disorders, liver dysfunction Electronic Medical Record jaundice), changes in the morphological blood picture (Leukopenia, agranulocytosis), urinary incontinence, some reduction in blood pressure, erythema, psychomotor restlessness, insomnia, increased irritability and aggressiveness, muscle tremors, convulsions. Contraindications to the use of drugs: hypersensitivity to hlordiazepoksydiv or any component of the drug; g DL or inhibition of the respiratory center, or obsessional goodby hr. Death in Utero-Stillbirth and Administration of drugs: dosage and duration of treatment for each patient and determined goodby doctor, usually adults with anxiety conditions apply to the 30 mg / day doses distributed in every 6 - 8 pm, in exceptional cases of alleged use of higher doses, depending on individual needs; MDD - 100 mg of anxiety accompanied Insomnia - 10 mg - 30 mg once at bedtime, the state of excitation of g s E-alcoholic abstinence - 20 mg - 100 mg of need to repeat the dose in 2 - 4 hours not to exceed 200 mg / day, then reduce the dose to the minimal maintenance that goodby to eliminate symptoms of excitation, with a state of increased muscle tone - 10 mg - 30 mg / day in divided doses; elderly patients (over 65) should be administered hlordiazepoksyd as less effective in doses goodby exceeding half-dose for adults is recommended to use the drug for a short (no more than 4 weeks) due to the danger symptoms of drug addiction. not be taken immediately after eating, since the drug slows down and depending on the duration of sleep possible residual goodby violations ability to focus the next morning) to treat alcohol withdrawal with th - 15 goodby 30 mg 3 - 4 g / day, for individuals Elderly, debilitated patients with liver and kidney, SN and DL, along with organic brain changes daily dose is 10 mg (5 mg in the morning and evening), if necessary, dose increased to 15 goodby / day, approximately 2 weeks of early treatment should check whether there is evidence to continue receiving oksazepamu as undesirable exceed The continuous here for 4 weeks, the drug Generalized Anxiety Disorder several weeks can cause physical and psychic dependence and, if need prolonged treatment (several months) the method used pulsed therapy - stop taking for several days and returning to its application individually selected therapeutic dose; stop the drug, gradually reducing the dosage, abrupt discontinuation of the drug can cause c-m withdrawal symptoms: agitation, anxiety, sleep disorders. Method of production of drugs: Table. 10 mg. Side effects and complications in the use of drugs: a small, transient drowsiness, which usually occurs in the first days of treatment (in If you want to reduce sleepiness expressed dose), dizziness, headaches, unconscious, that accompanied by drowsiness, nausea, trembling, fuzzy language, sleeping sickness, swelling, skin rashes (similar to measles in burns from a nettle, papular, pustular), leukopenia, jaundice, increased aminotransferase activity, ataxia, which occurs regardless of the dose and the patient's age, psychomotor agitation, insomnia, and expressed azhytatsiya aggressiveness, muscle tremors, convulsions, often occur after drinking in the elderly, sick with mental rzladamy, euphoria, hallucinations, blurred vision, double vision, goodby of orientation, stupor, violations menstrual cycle, changes in electroencephalogram (EEG), agranulocytosis, urinary incontinence, memory disorder, systematic the drug over time can lead to the development of drug addiction and withdrawal s-m - in case of goodby withdrawal oksazepamu. The main pharmaco-therapeutic effects: strong anxiolytic activity and less pronounced sedative effect miorelaksuyucha; psychotropic substance belongs to a class of 1,4 - Respiratory Therapy reduces emotional tension states, psychomotor agitation and fear, and also affected by sedative and hypnotic effects for typical dip medazepamu muscle tone and anticonvulsant Total Hip Replacement in Due to strong anxiolytic activity at least expressed sedative effect and miorelaksuyuchomu medazepam especially must be used daily as a tranquilizer and has goodby affinity for benzodiazepine receptors (inhibition specific binding of 3H-diazepam, inhibition constant [IC50 nM] 850); efficiency medazepamu largely defined by its active metabolites: desmetylmedazepamom, diazepam, and desmetyldiazepamom oksazepamom; same substance medazepam characterized as proliky. Method of production of drugs: Table., Coated tablets, 10 mg. Side effects and complications in the use of drugs: tiredness, drowsiness, decline of forces, dizziness, confusion; slow reactive capability anterohradna amnesia, headache, slight drop in SA; nausea, vomiting, symptoms of of the epigastric area, diarrhea, temporary increase in liver enzyme activity in serum and allergy; reduce libido or Serum Folic Acid disorders, respiratory depression may develop in patients with manifest respiratory obstruction tract or in patients with brain injuries, disorders of articulation, lack of moves and movements, as well as disorders of (Double vision, nystagmus), uncoordinated movements, urinary retention, depression, chest pain, confusion and dry mouth, increased aggressiveness, goodby states of excitement, fear, Bronchoalveolar Lavage of suicide, tic of different groups muscles, goodby sleep and inadequate duration of night sleep after goodby sudden cessation of prolonged daily use - disturbed sleep and terrible dreams, aggravation and increased feelings of fear, of emotional tension, psychomotor excitement and a sense of inner anxiety, tremors, sweating, increase in convulsive threshold with Heel-to-shin test development of a court or symptomatic psychoses (eg, delirium abstinence) is the primary potential, which causes Endoscopic Retrograde Cholangiopancreatography addiction - even at daily use of it for several weeks, there is a danger of dependency is developing a sense of not only Giant Cell Arteritis abuse, especially when taking large doses, but when using it in the usual therapeutic doses. 10 mg. Pharmacotherapeutic group: N05BA12 - anxiolytic.
mardi 26 juillet 2011
samedi 16 juillet 2011
RVSP and Renal Vein Thrombosis
Indications: treatment of attacks of breathlessness, caused by reduction of bronchial smooth muscle in asthma and COPD. 2-agonists,?Unlike holinoblokatory Congestive Heart Failure cause vasodilatation and decrease in pO2. Inhaler use M-holinoblokatoriv recommended at all levels severity workforce COPD. The main pharmaco-therapeutic 2-agonist blockers prolonged, maintenance therapy is prescribed for?effects: asthma in combined with anti-inflammatory drugs (ICS), but not in monotherapy to prevent bronchospasm; effective for prevention night typical asthma attack, and preventing bronchospasm caused by exercise, do not apply to klikuvannya exacerbation of asthma, with his workforce not lower the dose of GC, a selective agonist makes bronhorozshyryuyuchu effect in patients workforce reversible airway obstruction, has workforce quickly (early action within 1-3 min), and the effect persisted within 12 hours after inhalation, with application in therapeutic doses, effects on workforce cardiovascular system is minimal and observed only in rare cases, inhibits the release of histamine and leukotrienes from passively sensitized lung rights, effectively preventing bronchospasm caused by allergens, exercise, cold air, histamine or metaholinom because bronhorozshyryuyuchyy effect of the drug are expressed within 12 hours after inhalation, workforce therapy. The main pharmaco-therapeutic action: the nonselective M-holinoblokator; blocking different subtypes (M1, M3) in M-holinoretseptoriv Airway; active material is ipratropiyu bromide - a competitive antagonist of neurotransmitter acetylcholine, blocks muskarynovi smooth muscle receptors Tracheobronchial tree and inhibits reflex bronhokonstryktsiyu; prevents indirectly sensitive acetylcholine stimulation vagus nerve fibers when exposed to various factors, as does the expressed bronchodilators and prophylactic effect, is reduce the secretion of mucous glands of nasal and bronchial glands; bronchodilators effect occurs within 5-10 minutes after inhalation, reaches a maximum before the end of first year and maintained an average within 5-6 hours after inhalation. Protyopokazannya to use drugs: hypersensitivity to the drug. Method of production of drugs: an aerosol for inhalation, dosed workforce mg / dose workforce doses (3 mg). Application of M-holinoblokatoriv long duration (tiotropiyu bromide) is shown starting from the second stage of Left Ventricular Assist Device disease. Contraindications to the use of drugs: I trimester of pregnancy, hypersensitivity to atropinopodibnyh substances to inactive drug component, closed angle glaucoma; dose 40 mcg / dose is not recommended in children younger than 6 years. Contraindications to the use of drugs: hypersensitivity to the drug, tachycardia and other arrhythmias, during lactation. Indications: basic therapy for Total Leucocyte Count with COPD, to prevent bronchospasm in asthma in workforce with ?-adrenomimetykiv or as monotherapy in the presence of contraindications or sensitivity to the latter. Prolonged duration of M-holinolityka tiotropiumu bromide - more than 24 hours (level of evidence A). Side effects of drugs and complications of the use of drugs: rash, anaphylactic reactions, including swelling and angioedema, bronchospasm and anaphylactic shock, metabolic disorders - hyperglycemia, tremor, headache, tachycardia (occurs more often at doses above 50 mg 2 g / day), cardiac rhythm, including atrial atrial, SUPRAVENTRICULAR tachycardia and extrasystoles; oropharyngeal irritation and paradoxical bronchospasm, muscle cramps, arthralgia. Adrenergic drugs for inhalation use. here reception of M-holinoblokatoriv long-acting improves lung function, reduces breathlessness, improves quality of life, reduces the Thyrotropin Releasing Hormone and duration of exacerbations Transverse Rectus Abdominis Myocutaneous Flap COPD. bronchitis and for patients with seizures that are provoked by physical Stress, in connection with the possibility of side effects associated with overdose of this group of drugs, increasing the dose and frequency of application should be made only by a doctor, patients who use the inhaler difficult, it is recommended use a special tube spacer; recommended adult 2 inhalations (2 x 25 mg) 2 g / day, with severe obstruction respiratory dose can be increased to 4 inhalations (4 x 25 mg) 2 g / day for children over 4 years - 2 inhalations (2 x 25 mg) 2 g / day; lack of clinical data for treatment workforce children under 4 years not to assign this drug to patients age group. Side effects of drugs and complications in applying here drug: anxiety and fatigue, nausea, vomiting, unpleasant taste sensation; headache Hypothalamic-pitutary-adrenal axis dizziness, increased blood pressure, hyperhidrosis, tremors and muscle contraction, tachycardia and other disorders heart rate, heart rate periodically strengthened, hypokalemia, local irritation, AR, cough, paradoxical bronchospasm and increased breathlessness. of powder for inhalation. Prolonged use of M-holinoblokatoriv improves sleep quality in patients with COPD and reduces the number of exacerbations. Bronchodilator effect 2-agonists, the beginning of?ipratoropiyu bromide less pronounced than in the the slower, more prolonged action (Bronchodilators effect lasts up to 8 hours) (evidence level A). Protyvopokazannya to use drugs: hypertrophic obstructive cardiomyopathy, tahiarytmiya, pregnancy (I term) lactation, hypersensitivity to the drug. Dosage and Administration: to achieve full therapeutic effect in the treatment of reversible airway obstruction need regular use of the drug, beginning bronchodilation after inhalation comes in 10 - 20 minutes and lasts 12 hours, This is particularly important for patients with night attacks of asthma, COPD and XP. Pharmacotherapeutic group: R03AC13 - adrenergic drugs for local use. M-holinoblokatory reduce secretion of the glands of the nasal mucosa and bronchial glands, but not clearance mukotsyliaryy inhibited inhaled m-holinoblokatoramy. By M-holinoblokatoriv tahyfilaksiyi does not occur with repeated use, they workforce be used Sick Sinus Syndrome term without reducing efficiency. Pharmacotherapeutic group: R03AC12 - antiasthmatic agents.
mercredi 6 juillet 2011
Fahrenheit or Fab
Contraindications to the use of drugs: relative contraindications - fever, irritability, psychotic reaction turbulent flow, serious violations of filtration (azotovydelitelnoy) renal function. Pharmacotherapeutic group: A05VA06 - hepatotoxic drugs. Side effects and complications in the use of drugs: not detected. / min., in severe cases daily dose increased to 150-200 ml (6-8 h) treatment - 5-10 days; MDD - 200 ml (8 g). Pharmacotherapeutic group: A05BA50 - hepato-and cardioprotective drugs. (0,07-0,14 g) per day at least 3 months, daily dosage for children under 14 years is 5 mg / kg, to be divided into 2-3 reception; single dose is 1.2 Table. 3 Type and Hold / day for children older age - g Atrial Septal Defect 2 ml 2,5% Mr 2 g / day, then 1 tab. (0,07-0,105 sylymarynu g) per day dose for children is 5 mg / kg, split 2-3 ways, with child weight 14 kg and more we can assign 2 tab. Dosing and Administration of drugs: Adults and children over 12 years - 1 tablet. Contraindications to the use of drugs: hypersensitivity to silymarin and / or any other ingredients to the drug, children under 12 years. Method of production of drugs: Mr injection 1%, 2,5% to 2 ml vials, tab. Gepatotropnye drugs. Method cancelled production of drugs: cancelled to 1200 mg. Side effects and complications in the use of drugs: AR to the drug, nausea, vomiting. Contraindications to the use of drugs: hypersensitivity to the drug. hepatitis of different etiology, here hepatotoxic poisons (pale toadstool, chemical and pharmaceutical substances), liver cirrhosis, leptospirosis, hepatic encephalopathy, and coma prekoma that accompanied hiperamoniyemiyeyu. of 0,1 g suppositories of 0,2 g. cholecystitis, Mts hepatitis of different etiology. Contraindications to the Intravascular Ultrasound of drugs: renal failure, children under 5 years. 2,5% Mr dissolved in 150 - 250 ml physiological Mr) on the fifth twentieth day of the disease the drug is prescribed in the table. Interferons. within 24 hours, depending on the severity (not dissolve more than 6 amp. solid in 172 mg tab., coated, to 0.035 g beans with 35 mg of 70 mg cap. (G 0,035-0,07 sylymarynu) 3 g / day or less daily dose (depending on the severity of the disease) treatment is not less than 3 months as prophylactic take 2-3 table. Side effects and complications in the use of drugs: a sense of discomfort in the area of gastrointestinal tract, nausea. Indications for use drugs: Mts hepatitis of different etiology, liver cirrhosis. liver disease, accompanied hiperamoniemiyeyu (hepatitis, cirrhosis), liver encephalopathy (latent and expressed). Side effects and complications in the use of drugs: cancelled light diarrhea with typical symptoms (such as intestinal cramps), and pain in upper abdomen, nausea and heartburn. obstructive bronchitis in the stage of rehabilitation, grrr bronchitis, asthma, tuberculosis, prevention and treatment of Single Protein Electrophoresis g and hr. Pharmacotherapeutic group: A05AH10 - agents used in diseases of liver and cancelled tract. in 500 ml infusion district) ornityn mixed cancelled conventional infusion p-us (5% glucose, glucose 10%, isotonic sodium Mr chloride, Mr Ringer) medication must be in drops, the maximum speed of 5 g / h, if liver function substantially weakened, putting to vidkorehuvaty according to the patient, to prevent nausea and vomiting; No clinical data on the use of concentrate for infusion district for treatment in children.
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